Has regime change ever worked?
Rarely. Post-WWII Germany and Japan are the only clear successes, requiring massive occupation forces and decades of support. Modern attempts (Iraq, Libya, Afghanistan) have largely failed.
Who would govern Iran after regime change?
No viable alternative government exists. Iran has 6+ ethnic groups, no unified opposition, and 85 years of anti-Western sentiment. Analysts warn of Iraq-style power vacuum and sectarian conflict.